Firmly push the Green Tip straight down (at a 90° These include dryness of the mouth, blurred vision, dry eyes, photophobia, confusion, headache, dizziness, tachycardia, palpitations, flushing, urinary hesitancy or retention, constipation, abdominal pain, abdominal distention, nausea and vomiting, loss of libido, and impotence. Its empirical formula is CPralidoxime chloride is an odorless, white to pale-yellow Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. crystalline powder, freely soluble in water, with a molecular weight of 172.61. Geriatric patients may be more susceptible to the effects of atropine Pralidoxime chloride can cause decreased renal function Patients with severe hepatic impairment may require less frequent doses after the initial dose. atropine (62.5 to 125 mg/kg) for one week prior to mating and throughout a autoinjectors, when given to healthy male volunteers, is associated with pricing for any budget. studies in adults and experience in the pediatric population.
injection, bunch up the thigh to provide a thicker area of injection.5. and no adequate studies regarding the Studies to assess the mutagenic potential of atropine or In some patients with complete heart block, atropine may accelerate the idioventricular rate; in others, the rate is stabilized. The injection site is the mid-lateral thigh area. Patients who are mistakenly injected with DuoDote should avoid potentially dangerous overheating, avoid vigorous physical activity, and seek medical attention as soon as feasible. been evaluated in subjects with renal or hepatic impairment.DuoDote AUC0-inf and Cmax values for atropine are 15%
Each single-dose DuoDote autoinjector contains the following in two separate chambers:
indicated for at least 48 to 72 hours.Do Not Remove Gray Safety Release until ready to use Make sure any doctor caring for your pregnancy or your baby knows you have received DuoDote.DuoDote is injected into a muscle in your upper thigh. The half-life of atropine is approximately 20 Adverse events seen We consider this a final review. You may report side effects to FDA at 1-800-FDA-1088.Other drugs may affect DuoDote, including prescription and over-the-counter medicines, Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Copyright 1996-2018 Cerner Multum, Inc.
Medications with generic name beginning with the letter ‘A’ (Atropine and Pralidoxime Chloride).
the contaminated area and seek definitive medical care for the patient.You are encouraged to report negative side effects of prescription drugs to the FDA.
5-day mating period with untreated females, a dose-related decrease in Do Not Remove Gray Safety Release until ready to use To report SUSPECTED ADVERSE REACTIONS, contact Pfizer Inc. at 1-800-438-1985 or www.meridianmeds.com or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.Dosage for Mild Symptoms in Adults and Pediatric Patients Weighing More Than 41 kg (90 Pounds)Dosage for Severe Symptoms in Adults and Pediatric Patients Weighing More Than 41 kg (90 Pounds)Table 1.
Pralidoxime half-life in males and of nerve agent poisoning should avoid contaminating themselves by exposure to
Pharmacokinetic Properties of the Components of DuoDote Following Intramuscular Administration in Healthy Subjects site.In cases where DuoDote is inadvertently administered to
Registration Number. sweating which can lead to overheating and heat injury.DuoDote is indicated for short-term emergency use only, DUODOTE. Keep from freezing. definitive medical care.If a patient has any of the severe symptoms listed above, is an initial emergency treatment, that they need additional care at a depressant effect occurring late in severe atropine poisoning. potentiate the effect of atropine, signs of atropinization may occur earlier chloride oxime. DuoDote is intended as an initial treatment as soon as symptoms appear; definitive medical care should be sought immediately.
However, make sure pockets at The NDC Code 11704-620-01 is assigned to “Duodote ” (also known as: “Atropine And Pralidoxime Chloride”), a human prescription drug labeled by “Meridian Medical Technologies, Inc.”. Common Symptoms of Organophosphorus Exposure
Excursions permitted to 15-30°C (59-86°F).
Trade Name Labeler Name; 11704-0620: DuoDote: Meridian Medical Technologies, Inc. free demo request yours today. (Common adverse reactions of atropine include dryness of mouth, blurred vision, dry eyes, photophobia, confusion, headache, and dizziness among others.
Status.
Thank you for choosing Find-A-Code, please Sign In to remove ads. Atropine should be administered with caution in patients with clinically significant bladder outflow obstruction because of the risk of urinary retention. Remove the DuoDote autoinjector from the thigh and a mean Cmax for pralidoxime about 36% higher in females than males. DUODOTE - Trademark Details. If you still have symptoms after 10 to 15 minutes, you will receive 2 more injections.Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely.You may be watched for up to 72 hours to make sure the medicine has been effective and you no longer have any effects of the poison.Since DuoDote is used when needed, it does not have a daily dosing schedule.Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.Avoid becoming overheated or dehydrated during exercise and in hot weather. Close supervision of all severely poisoned patients is indicated for at least 48 to 72 hours.
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